Delayed effects of single neonatal subcutaneous exposure of low-dose 17α-ethynylestradiol on reproductive function in female rats
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چکیده
منابع مشابه
Delayed effects of neonatal exposure to Tween 80 on female reproductive organs in rats.
Neonatal female rats were injected ip (0.1 ml/rat) with Tween 80 in 1, 5 or 10% aqueous solution on days 4-7 after birth. Treatment with Tween 80 accelerated maturation, prolonged the oestrus cycle, and induced persistent vaginal oestrus. The relative weight of the uterus and ovaries was decreased relative to the untreated controls. Squamous cell metaplasia of the epithelial lining of the uteru...
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Background & Objective: Fennel, as an edible plant, and due to its estrogenic compounds, has widely been used as a therapeutic agent for centuries. In this study, the effects of neonatal exposure to fennel alcoholic extract (FAE), on the onset of puberty, estrus cycle, ovaries, and lordosis were investigated. Materials & Methods: In this experimental study, 48 female BALB/c pups were divid...
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Background Chlorpromazine (CPZ), an antipsychotic drug, is associated with increased risk of sexual dysfunction through increasing prolactin levels. The current study evaluates the effect of CPZ-induced hyperprolactinemia on ovarian follicular growth, gonadotropins, and alteration of ovarian source hormones. MaterialsAndMethods In this experimental study, animals were divided into four groups, ...
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nitric oxide (no) is a small molecule synthesized by most of mammalian cells with diverse biological activities including vasodilatation, host defense and wound healing. impaired wound healing is a common occurrence among diabetics and patients receiving glucocorticoid therapy. on the other hand the application of laser in biomedical area have been increased. thus, the current studies were desi...
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ژورنال
عنوان ژورنال: The Journal of Toxicological Sciences
سال: 2012
ISSN: 0388-1350,1880-3989
DOI: 10.2131/jts.37.681